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Popular Common Cancers

Kidney Cancer

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Kidney cancer -- also called renal cancer -- is a disease in which kidney cells become malignant (cancerous) and grow out of control, forming a tumor. Almost all kidney cancers first appear in the lining of tiny tubes (tubules) in the kidney. This type of kidney cancer is called renal cell carcinoma. The good news is that most of kidney cancers are found before they spread (metastasize) to distant organs. And cancers caught early are easier to treat successfully. However, these tumors can grow to be quite large before they are detected.

The kidneys are two bean-shaped organs, each about the size of a fist. They lie in your lower abdomen on each side of your spine. Their main job is to clean your blood, removing waste products and making urine.

Doctors don't know the causes of kidney cancer. But certain factors appear to increase the risk of getting kidney cancer. For example, kidney cancer occurs most often in people older than age 40. These are some other risk factors for kidney cancer:

  • Smoking . If you smoke cigarettes, your risk for kidney cancer is twice that of nonsmokers. Smokingcigars may also increase your risk.
  • Being male. Men are about twice as likely as women to get kidney cancer.
  • Being obese. Extra weight may cause changes to hormones that increase your risk.
  • Using certain pain medications for a long time. This includes over-the-counter drugs in addition to prescription drugs.
  • Having advanced kidney disease or being on long-term dialysis, a treatment for people with kidneys that have stopped working
  • Having certain genetic conditions, such as von Hippel-Lindau (VHL) disease or inherited papillary renal cell carcinoma
  • Having a family history of kidney cancer. The risk is especially high in siblings.
  • Being exposed to certain chemicals, such as asbestos, cadmium, benzene, organic solvents, or certain herbicides
  • Having high blood pressure. Doctors don't know whether high blood pressure or medication used to treat it is the source of the increased risk.
  • Being black. The risk in blacks is slightly higher than in whites. No one knows why.
  • Having lymphoma. For an unknown reason, there is an increased risk of kidney cancer in patients with lymphoma.

Having these risk factors does not mean you will get kidney cancer. And it's also true that you can have none of them and still get the disease.

What Are the Stages of Kidney Cancer?

Your prognosis depends on your general health, as well as the grade and stage of your kidney cancer.

These are the stages of kidney cancer. The higher the stage, the more advanced the cancer.

Stage I

  • A tumor 7 centimeters or smaller that is only in the kidney

Stage II

  • A tumor larger than 7 centimeters that is only in the kidney

Stage III

  • A tumor that is in the kidney and in at least one nearby lymph node
  • A tumor that is in the kidney's main blood vessel and may also be in nearby lymph node
  • A tumor that is in the fatty tissue around the kidney and may also involve nearby lymph nodes
  • A tumor that extends into major veins or perinephric tissues, but not into the ipsilateral adrenal gland and not beyond Gerota's fascia

Stage IV

  • Cancer has spread beyond the fatty layer of tissue around the kidney, and it may also be in nearby lymph nodes
  • Cancer may have spread to other organs, such as the bowel, pancreas, or lungs
  • Cancer has spread beyond Gerota's fascia (including contiguous extension into the ipsilateral adrenal gland)

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